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Drinkuth CR, Lehane MJ, Sartor GC. The effects of (2R,6R)-hydroxynorketamine on oxycodone withdrawal and reinstatement. Drug Alcohol Depend. 2023 Dec 1;253:110987. doi: 10.1016/j.drugalcdep.2023.110987. Epub 2023 Oct 5. PubMed PMID: 37864957; PubMed Central PMCID: PMC10842506.
Seyednejad SA, Sartor GC. Noncoding RNA therapeutics for substance use disorder. Adv Drug Alcohol Res. 2022;2. doi: 10.3389/adar.2022.10807. Epub 2022 Dec 20. PubMed PMID: 36601439; PubMed Central PMCID: PMC9808746.
Kasina V, Mownn RJ, Bahal R, Sartor GC. Nanoparticle delivery systems for substance use disorder. Neuropsychopharmacology. 2022 Jul;47(8):1431-1439. doi: 10.1038/s41386-022-01311-7. Epub 2022 Mar 28. Review. PubMed PMID: 35351961; PubMed Central PMCID: PMC8960682.
Singh MB, Babigian CJ, Sartor GC. Domain-selective BET inhibition attenuates transcriptional and behavioral responses to cocaine. Neuropharmacology. 2022 Jun 1;210:109040. doi: 10.1016/j.neuropharm.2022.109040. Epub 2022 Mar 18. PubMed PMID: 35314160; PubMed Central PMCID: PMC8986626.
Babigian CJ, Wiedner HJ, Wahlestedt C, Sartor GC. JQ1 attenuates psychostimulant- but not opioid-induced conditioned place preference. Behav Brain Res. 2022 Feb 10;418:113644. doi: 10.1016/j.bbr.2021.113644. Epub 2021 Oct 28. PubMed PMID: 34757001; PubMed Central PMCID: PMC8671323.
Singh MB, Sartor GC. BET bromodomains as novel epigenetic targets for brain health and disease. Neuropharmacology. 2020 Dec 15;181:108306. doi: 10.1016/j.neuropharm.2020.108306. Epub 2020 Sep 15. Review. PubMed PMID: 32946883; PubMed Central PMCID: PMC7655633.
Sartor GC. Epigenetic pharmacotherapy for substance use disorder. Biochem Pharmacol. 2019 Oct;168:269-274. doi: 10.1016/j.bcp.2019.07.012. Epub 2019 Jul 12. Review. PubMed PMID: 31306644; PubMed Central PMCID: PMC6733674.
Sartor GC, Malvezzi AM, Kumar A, Andrade NS, Wiedner HJ, Vilca SJ, Janczura KJ, Bagheri A, Al-Ali H, Powell SK, Brown PT, Volmar CH, Foster TC, Zeier Z, Wahlestedt C. Enhancement of BDNF Expression and Memory by HDAC Inhibition Requires BET Bromodomain Reader Proteins. J Neurosci. 2019 Jan 23;39(4):612-626. doi: 10.1523/JNEUROSCI.1604-18.2018. Epub 2018 Nov 30. PubMed PMID: 30504275; PubMed Central PMCID: PMC6343644.
Janczura KJ, Volmar CH, Sartor GC, Rao SJ, Ricciardi NR, Lambert G, Brothers SP, Wahlestedt C. Inhibition of HDAC3 reverses Alzheimer's disease-related pathologies in vitro and in the 3xTg-AD mouse model. Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):E11148-E11157. doi: 10.1073/pnas.1805436115. Epub 2018 Nov 5. PubMed PMID: 30397132; PubMed Central PMCID: PMC6255210.
Zhu W, Wang H, Wei J, Sartor GC, Bao MM, Pierce CT, Wahlestedt CR, Dykxhoorn DM, Dong C. Cocaine Exposure Increases Blood Pressure and Aortic Stiffness via the miR-30c-5p-Malic Enzyme 1-Reactive Oxygen Species Pathway. Hypertension. 2018 Apr;71(4):752-760. doi: 10.1161/HYPERTENSIONAHA.117.10213. Epub 2018 Feb 26. PubMed PMID: 29483230; PubMed Central PMCID: PMC5843539.
Sartor GC, Powell SK, Velmeshev D, Lin DY, Magistri M, Wiedner HJ, Malvezzi AM, Andrade NS, Faghihi MA, Wahlestedt C. Cocaine alters Homer1 natural antisense transcript in the nucleus accumbens. Mol Cell Neurosci. 2017 Dec;85:183-189. doi: 10.1016/j.mcn.2017.10.003. Epub 2017 Oct 18. PubMed PMID: 29055697; PubMed Central PMCID: PMC5698162.
Volmar CH, Salah-Uddin H, Janczura KJ, Halley P, Lambert G, Wodrich A, Manoah S, Patel NH, Sartor GC, Mehta N, Miles NTH, Desse S, Dorcius D, Cameron MD, Brothers SP, Wahlestedt C. M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer's disease genes and improving memory. Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9135-E9144. doi: 10.1073/pnas.1707544114. Epub 2017 Oct 9. PubMed PMID: 29073110; PubMed Central PMCID: PMC5664514.
Aziz AM, Brothers S, Sartor G, Holm L, Heilig M, Wahlestedt C, Thorsell A. The nociceptin/orphanin FQ receptor agonist SR-8993 as a candidate therapeutic for alcohol use disorders: validation in rat models. Psychopharmacology (Berl). 2016 Oct;233(19-20):3553-63. doi: 10.1007/s00213-016-4385-8. Epub 2016 Aug 11. PubMed PMID: 27515665; PubMed Central PMCID: PMC5021736.
Sartor GC, Powell SK, Wiedner HJ, Wahlestedt C, Brothers SP. Nociceptin receptor activation does not alter acquisition, expression, extinction and reinstatement of conditioned cocaine preference in mice. Brain Res. 2016 Feb 1;1632:34-41. doi: 10.1016/j.brainres.2015.11.044. Epub 2015 Dec 3. PubMed PMID: 26657743; PubMed Central PMCID: PMC4733396.
Magistri M, Velmeshev D, Makhmutova M, Patel P, Sartor GC, Volmar CH, Wahlestedt C, Faghihi MA. The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease. Curr Alzheimer Res. 2016;13(9):985-95. doi: 10.2174/1567205013666160427101832. PubMed PMID: 27117003; PubMed Central PMCID: PMC5026248.
Sartor GC, Powell SK, Brothers SP, Wahlestedt C. Epigenetic Readers of Lysine Acetylation Regulate Cocaine-Induced Plasticity. J Neurosci. 2015 Nov 11;35(45):15062-72. doi: 10.1523/JNEUROSCI.0826-15.2015. PubMed PMID: 26558777; PubMed Central PMCID: PMC4642238.
Sartor GC, Aston-Jones G. Post-retrieval extinction attenuates cocaine memories. Neuropsychopharmacology. 2014 Apr;39(5):1059-65. doi: 10.1038/npp.2013.323. Epub 2013 Nov 21. PubMed PMID: 24257156; PubMed Central PMCID: PMC3957116.
Sartor GC, Aston-Jones G. Regulation of the ventral tegmental area by the bed nucleus of the stria terminalis is required for expression of cocaine preference. Eur J Neurosci. 2012 Dec;36(11):3549-58. doi: 10.1111/j.1460-9568.2012.08277.x. Epub 2012 Oct 8. PubMed PMID: 23039920; PubMed Central PMCID: PMC3514627.
Sartor GC, St Laurent G 3rd, Wahlestedt C. The Emerging Role of Non-Coding RNAs in Drug Addiction. Front Genet. 2012;3:106. doi: 10.3389/fgene.2012.00106. eCollection 2012. PubMed PMID: 22737160; PubMed Central PMCID: PMC3381216.
Sartor GC, Aston-Jones GS. A septal-hypothalamic pathway drives orexin neurons, which is necessary for conditioned cocaine preference. J Neurosci. 2012 Mar 28;32(13):4623-31. doi: 10.1523/JNEUROSCI.4561-11.2012. PubMed PMID: 22457508; PubMed Central PMCID: PMC3350779.
Reissner KJ, Sartor GC, Vazey EM, Dunn TE, Aston-Jones G, Kalivas PW. Use of vivo-morpholinos for control of protein expression in the adult rat brain. J Neurosci Methods. 2012 Jan 30;203(2):354-60. doi: 10.1016/j.jneumeth.2011.10.009. Epub 2011 Oct 17. PubMed PMID: 22027492; PubMed Central PMCID: PMC3857614.
Mahler SV, Smith RJ, Moorman DE, Sartor GC, Aston-Jones G. Multiple roles for orexin/hypocretin in addiction. Prog Brain Res. 2012;198:79-121. doi: 10.1016/B978-0-444-59489-1.00007-0. Review. PubMed PMID: 22813971; PubMed Central PMCID: PMC3643893.
McGinty VB, Hayden BY, Heilbronner SR, Dumont EC, Graves SM, Mirrione MM, du Hoffmann J, Sartor GC, España RA, Millan EZ, Difeliceantonio AG, Marchant NJ, Napier TC, Root DH, Borgland SL, Treadway MT, Floresco SB, McGinty JF, Haber S. Emerging, reemerging, and forgotten brain areas of the reward circuit: Notes from the 2010 Motivational Neural Networks conference. Behav Brain Res. 2011 Nov 20;225(1):348-57. doi: 10.1016/j.bbr.2011.07.036. Epub 2011 Jul 26. Review. PubMed PMID: 21816177; PubMed Central PMCID: PMC3445023.
Cason AM, Smith RJ, Tahsili-Fahadan P, Moorman DE, Sartor GC, Aston-Jones G. Role of orexin/hypocretin in reward-seeking and addiction: implications for obesity. Physiol Behav. 2010 Jul 14;100(5):419-28. doi: 10.1016/j.physbeh.2010.03.009. Epub 2010 Mar 23. Review. PubMed PMID: 20338186; PubMed Central PMCID: PMC2886173.
Aston-Jones G, Smith RJ, Sartor GC, Moorman DE, Massi L, Tahsili-Fahadan P, Richardson KA. Lateral hypothalamic orexin/hypocretin neurons: A role in reward-seeking and addiction. Brain Res. 2010 Feb 16;1314:74-90. doi: 10.1016/j.brainres.2009.09.106. Epub 2009 Oct 6. Review. PubMed PMID: 19815001; PubMed Central PMCID: PMC2819557.
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